NTRK2 monoclonal antibody (M01), clone 4D3-F10
产品名称： NTRK2 monoclonal antibody (M01), clone 4D3-F10
英文名称： NTRK2 monoclonal antibody (M01), clone 4D3-F10
产品编号： H00004915-M01
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against a full length recombinant NTRK2.
- Immunogen:
- NTRK2 (AAH31835, 1 a.a. ~ 477 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
- Sequence:
- MSSWIRWHGPAMARLWGFCWLVVGFWRAAFACPTSCKCSASRIWCSDPSPGIVAFPRLEPNSVDPENITEIFIANQKRLEIINEDDVEAYVGLRNLTIVDSGLKFVAHKAFLKNSNLQHINFTRNKLTSLSRKHFRHLDLSELILVGNPFTCSCDIMWIKTLQEAKSSPDTQDLYCLNESSKNIPLANLQIPNCGLPSANLAAPNLTVEEGKSITLSCSVAGDPVPNMYWDVGNLVSKHMNETSHTQGSLRITNISSDDSGKQISCVAENLVGEDQDSVNLTVHFAPTITFLESPTSDHHWCIPFTVKGNPKPALQWFYNGAILNESKYICTKIHVTNHTEYHGCLQLDNPTHMNNGDYTLIAKNEYGKDEKQISAHFMGWPGIDDGANPNYPDVIYEDYGTAANDIGDTTNRSNEIPSTDVTDKTGREHLSVYAVVVIASVVGFCLLVMLFLLKLARHSKFGMKGFVLFHKIPLDG
- Host:
- Mouse
- Reactivity:
- Human
- Isotype:
- IgG2a Kappa
- Storage Buffer:
- In 1x PBS, pH 7.2
- Storage Instruction:
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (78.21 KDa) .
- MSDS:
Download
- Publication Reference
- 1.
- Peptide-mediated targeting of liposomes to TrkB receptor-expressing cells.
Ranjan S, Sood R, Dudas J, Glueckert R, Schrott-Fischer A, Roy S, Pyykko I, Kinnunen PK.Int J Nanomedicine. 2012;7:3475-85. Epub 2012 Jul 6.
- 2.
- Hypoxia-inducible Factor-1 (HIF-1) Is a Transcriptional Activator of the TrkB Neurotrophin Receptor Gene.
Martens LK, Kirschner KM, Warnecke C, Scholz H.J Biol Chem. 2007 May 11;282(19):14379-88. Epub 2007 Mar 20.
- Applications
- Western Blot (Recombinant protein)
- Protocol Download
- Sandwich ELISA (Recombinant protein)
- Detection limit for recombinant GST tagged NTRK2 is approximately 3ng/ml as a capture antibody.
- Protocol Download
- Application Image
- Western Blot (Recombinant protein)
- Sandwich ELISA (Recombinant protein)
- ELISA
- Entrez GeneID:
- 4915
- GeneBank Accession#:
- BC031835
- Protein Accession#:
- AAH31835
- Gene Name:
- NTRK2
- Gene Alias:
- GP145-TrkB,TRKB
- Gene Description:
- neurotrophic tyrosine kinase, receptor, type 2
- Omim ID:
- 600456
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation. Mutations in this gene have been associated with obesity and mood disorders. Alternate transcriptional splice variants encoding different isoforms have been found for this gene. [provided by RefSeq
- Other Designations:
- BDNF/NT-3 growth factors receptor,OTTHUMP00000021573,OTTHUMP00000021574,OTTHUMP00000021575,OTTHUMP00000021576,OTTHUMP00000021577,tyrosine kinase receptor B
- Gene Pathway
- Related Disease
- Alcoholism
- Alzheimer Disease
- Alzheimer disease
- Anorexia Nervosa
- Antisocial Personality Disorder
- Asperger Syndrome
- Attention Deficit Disorder with Hyperactivity
- Autistic Disorder
- Avoidance Learning
- Bipolar Disorder
- Bulimia
- Cardiovascular Diseases
- Cognition
- Depressive Disorder
- Depressive Disorder, Major
- Diabetes Mellitus, Type 2
- Disease Models, Animal
- Eating Disorders
- Edema