RNF7 (Human) Recombinant Protein (P01)
产品名称： RNF7 (Human) Recombinant Protein (P01)
英文名称： RNF7 (Human) Recombinant Protein (P01)
产品编号： H00009616-P01
产品价格： 0
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围： null
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Human RNF7 full-length ORF ( AAH05966, 1 a.a. - 113 a.a.) recombinant protein with GST-tag at N-terminal.
- Sequence:
- MADVEDGEETCALASHSGSSGSKSGGDKMFSLKKWNAVAMWSWDVECDTCAICRVQVMDACLRCQAENKQEDCVVVWGECNHSFHNCCMSLWVKQNNRCPLCQQDWVVQRIGK
- Theoretical MW (kDa):
- 38.17
- Preparation Method:
- in vitro wheat germ expression system
- Purification:
- Glutathione Sepharose 4 Fast Flow
- Storage Buffer:
- 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
- Storage Instruction:
- Store at -80°C. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- 12.5% SDS-PAGE Stained with Coomassie Blue.
- Note:
- Best use within three months from the date of receipt of this protein.
- MSDS:
Download
- Application Image
- Enzyme-linked Immunoabsorbent Assay
- Western Blot (Recombinant protein)
- Antibody Production
- Protein Array
- Entrez GeneID:
- 9616
- GeneBank Accession#:
- BC005966
- Protein Accession#:
- AAH05966
- Gene Name:
- RNF7
- Gene Alias:
- CKBBP1,ROC2,SAG
- Gene Description:
- ring finger protein 7
- Omim ID:
- 603863
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The protein encoded by this gene is a highly conserved ring finger protein. It is an essential subunit of SKP1-cullin/CDC53-F box protein ubiquitin ligases, which are a part of the protein degradation machinery important for cell cycle progression and signal transduction. This protein interacts with, and is a substrate of, casein kinase II (CSNK2A1/CKII). The phosphorylation of this protein by CSNK2A1 has been shown to promote the degradation of IkappaBalpha (CHUK/IKK-alpha/IKBKA) and p27Kip1(CDKN1B). Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq
- Other Designations:
- OTTHUMP00000180645,regulator of cullins 2,sensitive to apoptosis, zinc RING finger protein SAG, regulator of cullins 2,zinc RING finger protein SAG
- Gene Pathway