Caspase-8 Staining Kit (Red)
产品名称: Caspase-8 Staining Kit (Red)
英文名称: Caspase-8 Staining Kit (Red)
产品编号: KA0760
产品价格: 0
产品产地: 台湾
品牌商标: Abnova
更新时间: null
使用范围: null
亚诺法生技股份有限公司(Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Caspase-8 Staining Kit (Red) is used for sensitive detection of activated caspase-8 in living cells with sulfo-rhodamine.
- Reactivity:
- Mammals
- Storage Instruction:
- Store the kit at -20°C.
- Protocol:
- Protocol Download
- MSDS:
- Download
- Suitable Sample:
- Cell
- Detection Method:
- Fluorometric
- Regulation Status:
- For research use only (RUO)
- Application Image
- Functional Study
- Flow Cytometry
- Entrez GeneID:
- 841
- Gene Name:
- CASP8
- Gene Alias:
- ALPS2B,CAP4,FLICE,FLJ17672,MACH,MCH5,MGC78473
- Gene Description:
- caspase 8, apoptosis-related cysteine peptidase
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes composed of a prodomain, a large protease subunit, and a small protease subunit. Activation of caspases requires proteolytic processing at conserved internal aspartic residues to generate a heterodimeric enzyme consisting of the large and small subunits. This protein is involved in the programmed cell death induced by Fas and various apoptotic stimuli. The N-terminal FADD-like death effector domain of this protein suggests that it may interact with Fas-interacting protein FADD. This protein was detected in the insoluble fraction of the affected brain region from Huntington disease patients but not in those from normal controls, which implicated the role in neurodegenerative diseases. Many alternatively spliced transcript variants encoding different isoforms have been described, although not all variants have had their full-length sequences determined. [provided by RefSeq
- Other Designations:
- FADD-homologous ICE/CED-3-like protease,MACH-alpha-1/2/3 protein,MACH-beta-1/2/3/4 protein,Mch5 isoform alpha,OTTHUMP00000163718,OTTHUMP00000163719,OTTHUMP00000163720,caspase 8,caspase 8, apoptosis-related cysteine protease,cysteine protease,procaspase-8
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