PDGFRA monoclonal antibody, clone 16A1 (PE)
产品名称: PDGFRA monoclonal antibody, clone 16A1 (PE)
英文名称: PDGFRA monoclonal antibody, clone 16A1 (PE)
产品编号: MAB9804
产品价格: null
产品产地: 台湾
品牌商标: Abnova
更新时间: null
使用范围:
亚诺法生技股份有限公司(Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against PDGFRA.
- Immunogen:
- Human PDGFRA transfected NIH/3T3 cells.
- Host:
- Mouse
- Theoretical MW (kDa):
- 170
- Reactivity:
- Human
- Specificity:
- The mouse monoclonal antibody 16A1 recognizes PDGFRA (CD140a), the 170 kDa alpha chain of platelet-derived growth factor receptor, which is widely expressed on a variety of mesenchymal-derived cells and plays pro-proliferative or anti-proliferative roles in various tumours.
- Form:
- Liquid
- Conjugation:
- PE
- Purification:
- Size-exclusion chromatography purification
- Isotype:
- IgG1
- Storage Buffer:
- In PBS, pH 7.4 (0.02% BSA, 15 mM sodium azide)
- Storage Instruction:
- Store in the dark at 4°C. Avoid prolonged exposure to light. Do not freeze.
- Recommend Usage:
- Flow Cytometry (20 uL reagent/100 uL of whole blood or 106 cells)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Application Image
- Flow Cytometry
- Entrez GeneID:
- 5156
- Gene Name:
- PDGFRA
- Gene Alias:
- CD140A,MGC74795,PDGFR2,Rhe-PDGFRA
- Gene Description:
- platelet-derived growth factor receptor, alpha polypeptide
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. Studies in knockout mice, where homozygosity is lethal, indicate that the alpha form of the platelet-derived growth factor receptor is particularly important for kidney development since mice heterozygous for the receptor exhibit defective kidney phenotypes. [provided by RefSeq
- Other Designations:
- FIP1L1/PDGFRA fusion protein,platelet-derived growth factor receptor alpha,rearranged-in-hypereosinophilia-platelet derived growth factor receptor alpha fusion protein
- Related Disease