TGFBI monoclonal antibody, clone k1H12
产品名称： TGFBI monoclonal antibody, clone k1H12
英文名称： TGFBI monoclonal antibody, clone k1H12
产品编号： MAB2058
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against partial recombinant TGFBI.
- Immunogen:
- Recombinant protein corresponding to amino acids 502-636 of human TGFBI.
- Host:
- Mouse
- Reactivity:
- Human, Mouse
- Form:
- Liquid
- Isotype:
- IgG2a, kappa
- Storage Buffer:
- In PBS, pH 7.4 (0.1% sodium azide)
- Storage Instruction:
- Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Recombinant Protein.
- Recommend Usage:
- The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- The transforming growth factor-beta-inducible matrix protein (beta)ig-h3 interacts with fibronectin.
Billings PC, Whitbeck JC, Adams CS, Abrams WR, Cohen AJ, Engelsberg BN, Howard PS, Rosenbloom J.J Biol Chem. 2002 Aug 2;277(31):28003-9. Epub 2002 May 28.
- 2.
- BIGH3 mutation spectrum in corneal dystrophies.
Munier FL, Frueh BE, Othenin-Girard P, Uffer S, Cousin P, Wang MX, Heon E, Black GC, Blasi MA, Balestrazzi E, Lorenz B, Escoto R, Barraquer R, Hoeltzenbein M, Gloor B, Fossarello M, Singh AD, Arsenijevic Y, Zografos L, Schorderet DF.Invest Ophthalmol Vis Sci. 2002 Apr;43(4):949-54.
- 3.
- Identification of motifs for cell adhesion within the repeated domains of transforming growth factor-beta-induced gene, betaig-h3.
Kim JE, Kim SJ, Lee BH, Park RW, Kim KS, Kim IS.J Biol Chem. 2000 Oct 6;275(40):30907-15.
- Applications
- Western Blot
- Cell lysates of HeLa (lane 1), Jurkat (lane 2), 293T (lane 3) and the extracts of mouse liver tissue (lane 4) (20 ug) were resolved by SDS-PAGE and probed with TGFBI monoclonal antibody, clone k1H12 (Cat # MAB2058) (1:1000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system.
- Entrez GeneID:
- 7045
- Protein Accession#:
- NP_000349
- Gene Name:
- TGFBI
- Gene Alias:
- BIGH3,CDB1,CDG2,CDGG1,CSD,CSD1,CSD2,CSD3,EBMD,LCD1
- Gene Description:
- transforming growth factor, beta-induced, 68kDa
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes an RGD-containing protein that binds to type I, II and IV collagens. The RGD motif is found in many extracellular matrix proteins modulating cell adhesion and serves as a ligand recognition sequence for several integrins. This protein plays a role in cell-collagen interactions and may be involved in endochondrial bone formation in cartilage. The protein is induced by transforming growth factor-beta and acts to inhibit cell adhesion. Mutations in this gene are associated with multiple types of corneal dystrophy. [provided by RefSeq
- Other Designations:
- RGD-containing collagen-associated protein,kerato-epithelin