NFATC1 (Human) Recombinant Protein (Q01)
产品名称: NFATC1 (Human) Recombinant Protein (Q01)
英文名称: NFATC1 (Human) Recombinant Protein (Q01)
产品编号: H00004772-Q01
产品价格: 0
产品产地: 台湾
品牌商标: Abnova
更新时间: null
使用范围: null
亚诺法生技股份有限公司(Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Human NFATC1 partial ORF ( NP_006153, 701 a.a. - 810 a.a.) recombinant protein with GST-tag at N-terminal.
- Sequence:
- IKTEPTDDYEPAPTCGPVSQGLSPLPRPYYSQQLAMPPDPSSCLVAGFPPCPQRSTLMPAAPGVSPKLHDLSPAAYTKGVASPGHCHLGLPQPAGEAPAVQDVPRPVATH
- Theoretical MW (kDa):
- 37.84
- Preparation Method:
- in vitro wheat germ expression system
- Purification:
- Glutathione Sepharose 4 Fast Flow
- Storage Buffer:
- 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
- Storage Instruction:
- Store at -80°C. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- 12.5% SDS-PAGE Stained with Coomassie Blue.
- Note:
- Best use within three months from the date of receipt of this protein.
- MSDS:
- Download
- Application Image
- Enzyme-linked Immunoabsorbent Assay
- Western Blot (Recombinant protein)
- Antibody Production
- Protein Array
- Entrez GeneID:
- 4772
- GeneBank Accession#:
- NM_006162
- Protein Accession#:
- NP_006153
- Gene Name:
- NFATC1
- Gene Alias:
- MGC138448,NF-ATC,NFAT2,NFATc
- Gene Description:
- nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
- Omim ID:
- 600489
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The product of this gene is a component of the nuclear factor of activated T cells DNA-binding transcription complex. This complex consists of at least two components: a preexisting cytosolic component that translocates to the nucleus upon T cell receptor (TCR) stimulation, and an inducible nuclear component. Proteins belonging to this family of transcription factors play a central role in inducible gene transcription during immune response. The product of this gene is an inducible nuclear component. It functions as a major molecular target for the immunosuppressive drugs such as cyclosporin A. Five transcript variants encoding distinct isoforms have been identified for this gene. Different isoforms of this protein may regulate inducible expression of different cytokine genes. [provided by RefSeq
- Other Designations:
- NFAT transcription complex cytosolic component,nuclear factor of activated T-cells, cytosolic component 1