PODXL polyclonal antibody
产品名称： PODXL polyclonal antibody
英文名称： PODXL polyclonal antibody
产品编号： PAB12068
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of PODXL.
- Immunogen:
- A synthetic peptide corresponding to amino acids 350-450 of human PODXL.
- Host:
- Rabbit
- Reactivity:
- Human
- Form:
- Liquid
- Storage Buffer:
- In Tris-glycine, 150 mM NaCl (0.05% sodium azide)
- Storage Instruction:
- Store at -20°C or -80°C.
Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Synthetic Peptide.
- Recommend Usage:
- Western Blot (2 ug/mL)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Podocalyxin variants and risk of prostate cancer and tumor aggressiveness.
Casey G, Neville PJ, Liu X, Plummer SJ, Cicek MS, Krumroy LM, Curran AP, McGreevy MR, Catalona WJ, Klein EA, Witte JS.Hum Mol Genet. 2006 Mar 1;15(5):735-41. Epub 2006 Jan 24.
- 2.
- Podocalyxin: a marker of blasts in acute leukemia.
Kelley TW, Huntsman D, McNagny KM, Roskelley CD, Hsi ED.Am J Clin Pathol. 2005 Jul;124(1):134-42.
- 3.
- Overexpression of the anti-adhesin podocalyxin is an independent predictor of breast cancer progression.
Somasiri A, Nielsen JS, Makretsov N, McCoy ML, Prentice L, Gilks CB, Chia SK, Gelmon KA, Kershaw DB, Huntsman DG, McNagny KM, Roskelley CD.Cancer Res. 2004 Aug 1;64(15):5068-73.
- Entrez GeneID:
- 5420
- Protein Accession#:
- O00592
- Gene Name:
- PODXL
- Gene Alias:
- Gp200,MGC138240,PC,PCLP
- Gene Description:
- podocalyxin-like
- Omim ID:
- 602632
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a member of the sialomucin protein family. The encoded protein was originally identified as an important component of glomerular podocytes. Podocytes are highly differentiated epithelial cells with interdigitating foot processes covering the outer aspect of the glomerular basement membrane. Other biological activities of the encoded protein include: binding in a membrane protein complex with Na+/H+ exchanger regulatory factor to intracellular cytoskeletal elements, playing a role in hematopoetic cell differentiation, and being expressed in vascular endothelium cells and binding to L-selectin. [provided by RefSeq
- Other Designations:
- -