TNFRSF1B (Human) Recombinant Protein
产品名称： TNFRSF1B (Human) Recombinant Protein
英文名称： TNFRSF1B (Human) Recombinant Protein
产品编号： H00007133-H01
产品价格： 0
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围： null
亚诺法生技股份有限公司（Abnova)
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- 邮编 : 11493
- 所在区域 : 台湾
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- Specification
- Product Description:
- Purified TNFRSF1B (AAH52977.1 23 a.a. - 257 a.a.) human recombinant protein with His-Flag-StrepII tag at N-terminus expressed in human cells.
- Transfected Cell Line:
- Human HEK293T cells
- Sequence:
- LPAQVAFTPYAPEPGSTCRLREYYDQTAQMCCSKCSPGQHAKVFCTKTSDTVCDSCEDSTYTQLWNWVPECLSCGSRCSSDQVETQACTREQNRICTCRPGWYCALSKQEGCRLCAPLRKCRPGFGVARPGTETSDVVCKPCAPGTFSNTTSSTDICRPHQICNVVAIPGNASMDAVCTSTSPTRSMAPGAVHLPQPVSTRSQHTQPTPEPSTAPSTSFLLPMGPSPPAEGSTGD
- Host:
- Human
- Theoretical MW (kDa):
- 31.13
- Form:
- Liquid
- Preparation Method:
- Transfection of pSuper-TNFRSF1B plasmid into HEK293T cell, and the expressed protein was purified by Strep-Tactin affinity column.
- Purification:
- Strep-Tactin affinity columns
- Concentration:
- > 10 ug/ml
- Activity:
- Not Tested
- Storage Buffer:
- 100 mM Tris-HCl pH 8.0, 150 mM NaCl, 1 mM EDTA, and 5 mM desthiobiotin.
- Storage Instruction:
- Store at -80°C. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- SDS-PAGE and Western Blot
SDS-PAGE Gel
Western Blot
- Application Image
- Western Blot
- Enzyme-linked Immunoabsorbent Assay
- SDS-PAGE
- Protein Interaction
- Entrez GeneID:
- 7133
- GeneBank Accession#:
- BC052977.1
- Protein Accession#:
- AAH52977.1
- Gene Name:
- TNFRSF1B
- Gene Alias:
- CD120b,TBPII,TNF-R-II,TNF-R75,TNFBR,TNFR1B,TNFR2,TNFR80,p75,p75TNFR
- Gene Description:
- tumor necrosis factor receptor superfamily, member 1B
- Omim ID:
- 191191
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The protein encoded by this gene is a member of the TNF-receptor superfamily. This protein and TNF-receptor 1 form a heterocomplex that mediates the recruitment of two anti-apoptotic proteins, c-IAP1 and c-IAP2, which possess E3 ubiquitin ligase activity. The function of IAPs in TNF-receptor signalling is unknown, however, c-IAP1 is thought to potentiate TNF-induced apoptosis by the ubiquitination and degradation of TNF-receptor-associated factor 2, which mediates anti-apoptotic signals. Knockout studies in mice also suggest a role of this protein in protecting neurons from apoptosis by stimulating antioxidative pathways. [provided by RefSeq
- Other Designations:
- OTTHUMP00000001784,p75 TNF receptor,soluble TNFR1B variant 1,tumor necrosis factor beta receptor,tumor necrosis factor binding protein 2,tumor necrosis factor receptor 2
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