1) Cat. No.: TRC-S590250; 2) Chemical Name: SNX-2112; 3) CAS No.: 908112-43-6; 4) Mol. Formula: C23H27F3N4O3; 5) Mol. Weight: 464.48; 6) Packing Size: 5mg / 10mg; 7) Appearence: ; 8) Application Notes: SNX-2112 is a selective heat shock protein 90 (Hsp90) inhibitor which can exert a potent anticancer activity. Studies demonstates that SNX-2112 can exhibit a potent anticancer activity against B16 melanoma cells both in vitro and in vivo, by inhibiting cell proliferation and inducing cell cycle arrest and apoptosis in a mechanism dependent on the degredation of Hsp90 client proteins.; 9) Synonym: 4-(6,6-Dimethyl-4-oxo-3-(trifluoromethyl)-4,5,6,7-tetrahydroindazol-1-yl)-2-((1r,4r)-4-hydroxycyclohexylamino)benzamide; PF 04928473;; 10) Solubility: ; 11) Storage condition: ; 12) References: Liu, K.S., et al.: Oncol. Reports., 27, 1904 (2012); Wang, S.X., et al.: BioSci. Biotech. Biochem., 75, 1540 (2011); Bachleitner, H., et al.: Clinical, Cancer, Rsch., 17, 12 (2011);