DNMT1 (phospho S714) Peptide
产品名称： DNMT1 (phospho S714) Peptide
英文名称： DNMT1 (phospho S714) Peptide
产品编号： P1649
产品价格： 0
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围： null
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic phosphopeptide of DNMT1.
- Immunogen:
- Synthetic phosphopeptide (conjugated with KLH) corresponding to residues surrounding S714 of human DNMT1.
- Host:
- Rabbit
- Reactivity:
- Human
- Form:
- Liquid
- Purification:
- Protein A purification
- Storage Buffer:
- In PBS (0.09% sodium azide)
- Storage Instruction:
- Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- ELISA (1:1000)
Dot Blot (1:500)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Double RNA interference of DNMT3b and DNMT1 enhances DNA demethylation and gene reactivation.
Leu YW, Rahmatpanah F, Shi H, Wei SH, Liu JC, Yan PS, Huang TH.Cancer Res. 2003 Oct 1;63(19):6110-5.
- 2.
- p53-mediated repression of DNA methyltransferase 1 expression by specific DNA binding.
Peterson EJ, Bogler O, Taylor SM.Cancer Res. 2003 Oct 15;63(20):6579-82.
- 3.
- Increased protein expression of DNA methyltransferase (DNMT) 1 is significantly correlated with the malignant potential and poor prognosis of human hepatocellular carcinomas.
Saito Y, Kanai Y, Nakagawa T, Sakamoto M, Saito H, Ishii H, Hirohashi S.Int J Cancer. 2003 Jul 1;105(4):527-32.
- Entrez GeneID:
- 1786
- Protein Accession#:
- NP_001370;P26358
- Gene Name:
- DNMT1
- Gene Alias:
- AIM,CXXC9,DNMT,FLJ16293,MCMT,MGC104992
- Gene Description:
- DNA (cytosine-5-)-methyltransferase 1
- Omim ID:
- 126375
- Gene Ontology:
- Hyperlink
- Gene Summary:
- DNA (cytosine-5-)-methyltransferase 1 has a role in the establishment and regulation of tissue-specific patterns of methylated cytosine residues. Aberrant methylation patterns are associated with certain human tumors and developmental abnormalities. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
- Other Designations:
- CXXC finger protein 9,DNA methyltransferase 1
- Gene Pathway
- Related Disease